Oscar's Paediatric Brain Tumour Charity

Grades of brain tumours

grades of brain tumours can vary. This image shows a young girl with a head bandage looking sad and holding a teddy
Not all tumours are the same

What do brain tumour ‘grades’ mean?

When your child is diagnosed with a brain tumour, it’s natural for parents to fear the worst.

But remember that not all tumours are the same, and your child’s treatment will depend on a lot of factors.

One important thing to understand is the ‘grade’ of the tumour, which is how doctors describe how aggressive the tumour may be.

Useful Information about

Brain Tumour Grades

Brain tumours are classified into different grades based on how the cells look when examined under a microscope. The grades help doctors understand how fast the tumour may grow, and how likely it is to spread to other parts of the brain or body.

Low-grade (Grade 1 and 2) tumours

Low-grade tumours are generally slow-growing, non-malignant and less aggressive. Grade 1 tumours have cells that closely resemble normal brain cells, while Grade 2 tumours have slightly more abnormal cells but still tend to grow slowly. These tumours are less likely to spread to other parts of the brain or body.
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High-grade (Grade 3 and 4) tumours

High-grade tumours are known as malignant, are more aggressive and tend to grow faster. Grade 3 tumours have cells that appear more abnormal, and Grade 4 tumours have the most abnormal cells. These tumours are more likely to spread to nearby brain tissue or other areas of the brain or spinal cord.

The specific grades may vary depending on the type of brain tumour your child has. Gliomas can range from grade 1 to 4, ependymomas from grades 1 to 3. All medulloblastoma tumours are considered grade 4.

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How does the doctor know which grade my child’s tumour is?

To determine the grade, a specialist called a pathologist examines a sample of the tumour. This sample will have come from your child’s biopsy or surgery. The pathologist will study the tumour cells under a microscope to identify their characteristics and work out its grade.

The grade of the tumour provides essential information for developing an appropriate and personalised treatment plan for your child. For low-grade tumours, treatment options may include surgery or observation. High-grade tumours may require more aggressive treatments like surgery, chemotherapy, and radiotherapy to remove or control the tumour. Your child’s treatment plan will be created especially for them, their particular type of tumour and its position in the brain.

Along with the grades of brain tumours, it is also important to understand the type of brain tumour. A basic understanding of the different types of brain tumours can be crucial in making the best possible decisions for your child. It can also give you more confidence when talking to medical staff. To learn more about the different types of tumour please check out this page here.

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‘Benign’ or malignant – what does this mean?

Doctors may use these terms to refer to your child’s tumour. Your specialist may describe a low-grade tumour as non-malignant or benign, which means it is non-cancerous. These types of tumours tend to grow slowly, and are less likely to spread to other parts of the brain or spinal cord. The term ‘benign’ is used less often as it can be misleading. Despite not being cancerous, these tumours can still cause issues as they can put pressure on the brain, spinal cord or optic nerve.

A high-grade tumour can also be called a malignant tumour. This is cancerous, and its cells appear very abnormal under a microscope. These types of tumours are more aggressive and can spread to other parts of the brain and spinal cord. These often require radiotherapy or chemotherapy for treatment.

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How we help

AWARENESS

Raising Awareness: We’re passionate about spreading awareness. Our efforts extend to schools, colleges, and businesses, where we engage in assemblies and workshops. By working closely with such places, we ensure that paediatric brain tumours are understood, recognised, and acknowledged by the people they could affect.

Signs and Symptoms: We’re reaching out to schools, parents, and communities to provide easily accessible knowledge that helps individuals to identify signs and symptoms to aid early diagnosis.

Collaboration with Other Charities: Our mission is bolstered by collaboration. We work hand in hand with other brain tumour and childhood cancer charities, pooling resources and expertise to maximise our collective impact. Together, we’re a formidable force for change.

How we help

Support & Care

Family Support Packages:  Our family vouchers have included funded physiotherapy sessions and mental health support. We aim to tailor our provision to your needs

Advice: We’re here to be a constant pillar of strength. We provide a safe space to share experiences, challenges, and triumphs. We understand the emotional journey and families find solace in knowing they’re not alone.

Information pages: Our extensive information pages help guide families through complex decisions related to diagnosis, treatment and beyond. We’re here to ensure that every family is equipped with the information they need to make the best choices for their child.

Communication Support: We understand that clear communication is key. We assist families in navigating conversations with healthcare professionals, ensuring they’re empowered to ask questions and fully understand the medical aspects of their child’s journey.

Connecting Families: We foster connections by bringing families in similar situations together. This shared understanding creates a strong support system where experiences are shared, advice is given, and bonds are formed.

Booster Boxes: Our thoughtfully-chosen individualised Booster Boxes are available for children affected and their siblings. Filled with goodies, these boxes provide a little cheer during challenging times.   

Do You Need Any Help Or Assistance?

Rachel James

Community Fundraising Assistant
Rachel will join our team on September 1st and will be doing a wide range of tasks including promoting the charity in the local community, developing relationships with different people and organisations, and finding new fundraising opportunities. She comes from a caring background having been a teaching assistant and emotional literacy support assistant in York for many years, and previously leading a community care team. She has also done many years of work in the voluntary sector.

Matthew Taylor

Trustee

Matthew Taylor is Director of the York Health Economics Consortium at the University of York. He has been a supporter of OSCAR’s since its inception and, through his twenty years of research into the measurement of health-related quality of life, Matthew is keenly aware of the huge benefits that new treatments can bring to people living with brain tumours.

Matthew is actively involved in national-level healthcare decision making, having had former roles as the Scientific Director of the National Institute for Health and Care Excellence (NICE)’s Economic and Methodological Unit and as a committee member for NICE’s Public Health Advisory Group. He has over fifty peer-reviewed scientific publications, including a chapter in the textbook ‘The Business, Policy and Economics of Neurosurgery’.

Ryan Mathew

Clinical Trustee

Ryan Mathew is an Associate Professor at the University of Leeds and an Honorary Consultant Neurosurgeon at Leeds Teaching Hospitals.

The Hughes Family story had a big impact on Ryan. He first learnt of the charity when he became surgeon to Oscar’s dad, Ian. After a successful surgery, he continued to show great care and concern for the family when Ian became ill again and when Milo, Oscar’s brother, was diagnosed with a brain tumour. Ryan is driven to make life outcomes better for brain tumour patients and their families. His extensive work in both research and surgery is testament to that commitment.

His clinical practice covers the full spectrum of general neurosurgery with a subspecialty in brain tumours. His research focuses on advanced brain tumour models, residual therapy-resistant glioma cell populations, local therapeutic treatments and surgical technologies and devices. He peer-reviews for several journals and grant award committees and has published numerous papers.

More information on Ryan’s work

Lisa Dawson

Trustee

Lisa has been a friend of the Hughes family since 2016 and was honoured to be asked in 2022 to represent OSCAR’s PBTC as Social & Digital Trustee.  Both Lisa and her family have taken part in numerous fundraising events and are dedicated to raising awareness of paediatric brain tumours.  Lisa is a social media content creator, blogger and writer and lives in York with her husband Joe and three children, Ella, Max and Leo.

Alice Beckwith

Trustee

Alice has been involved with OSCAR’s PBTC since 2020. She passionately supports the aims of the charity and believes that if the charity can change one life for the better, then it is a success. Working in the public sector for 18 years, Alice has helped transform Adult and Children’s Social Care Services by ensuring heavy investment in preventative services. This is why the impact OSCAR’s work will have on families is at the forefront of Alice’s motivation to be involved.

As partnerships trustee, Alice is keen to involve businesses, trusts and individuals in the work OSCAR’s does and show them the role they can have in providing the base for the charity to continue to expand its projects to help children with brain tumours.

Sarah Jane Gray

Trustee/Secretary

Sarah has over 20 years of experience in the pharmaceutical and surgical sales sector and is very familiar with the importance of medical advancements for better patient outcomes. She believes research is essential for improving diagnosis, treatment and prognosis for all children with brain tumours and hopes OSCAR’s PBTC can offer much needed funding to help push the boundaries in finding better ways of curing this devastating disease. Sarah’s focus as a treasurer will ensure record-keeping and accounts meet the conditions of the statutory bodies and compliance with regulatory organisations.

Holly Dixon

Trustee

Holly is mother to George, diagnosed with an ATRT brain tumour in 2022, and works as a primary school teacher. She believes that action to support others -however small- can make a massive difference.


She brings real-life experience of what it is like for a parent navigating everyday life, the NHS, the education system, questions from people and a lively young child with different needs.

meet the oscar's team

Sam Marino

Trustee

Marie Hughes

ChAIR OF THE BOARD OF TRUSTEES

Marie founded the charity with her husband Ian, who passed away in 2020. She is the mother of four boys. Two of Marie’s sons have died from different types of brain tumours – Oscar who was 9 and Milo who was 5 years old. She is determined to help find better treatments for brain tumours so other children won’t have to go through what her own sons and her family have.

Marie is Chair of the Board of Trustees, working closely withe the team on strategy and vision. Marie lives in Copenhagen with her two other sons, Sebastian and Lucas, and works as a Risk Manager on the Danish railway.